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frank faded â??Whatâ??s important in biology is not that you have the right sequence to your DNA, but you have the right balance of DNA,â? Lawrence said. â??Women have two X chromosomes and men have one X and Y. Since the Y chromosome lacks a lot of the genes in the X chromosomes, women have more expression of X chromosome genes than men â?? well that wouldnâ??t work biologically. So nature had to devise a mechanism to equalize that.â?